PerFem Forte™ - Research Brief

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References

Low USA domestic & international


Indication: menopausal syndrome, hormonal imbalance, cardio-vascular and nervous system support, prevention of osteoporosis and cancer of the female reproductive organs.

Actions: normalizes  the balance of female hormones, relieves symptoms of menopause, antioxidant defense, prevents aging, promotes healthy nervous and  cardiovascular systems, increases endurance and work capacity, has a beneficial impact on appearance.

Ingredients (per 1 packet): Vitamin E (as d-alpha-tocopheryl succinate) - 15 IU, Thiamin (as thiamin mononitrate) - 1 mg,  Riboflavin - 1 mg, Niacin (as niacinamide) - 10 mg, Vitamin B6 (as pyridoxine HCl) - 3 mg, Folate - 200 mcg, Vitamin B12 (as cyanocobalamin) - 3 mcg, Selenium (as selenium + GMP™) - 35 mcg,  Fermented (aglycone) VDF Isoflavones™ (from organic GMO-Free soybean extract and GMO-Free red clover extract (aerial parts))- 25.5 mg, Black cohosh (Cimicifuga foetida) (12:1) root extract [(8% triterpene glycosides (as 27-deoxyactein)] (equivalent to 150 mg of crude herb) - 12.5 mg.


PerFem Forte™ - Research Brief:

Vitamin E helps prevent arteries from clogging, thins the blood, allowing for blood to flow more easily through arteries.  Studies in the last 10 years have reported beneficial results from use of vitamin E supplements as part of a prevention strategy for cardiovascular disease. 

Vitamin E is very beneficial for women during the menopause years. (1) 
Vitamin E
is effective for the reduction of hot flashes, night sweats, mood swings and even vaginal dryness.  Vitamin E also helps reduce long term risks associated with menopause such as Alzheimer’s, macular degeneration, and cardiovascular disease. A study of postmenopausal women suggested that vitamin E may reduce the risk of death from stroke in postmenopausal women.
PerFem Forte™ contains folic acid

Selenium+GPM™ is a nutritional ingredient especially developed for better absorption and increased safety. A proprietary, multi-stage fermentation process is used to create its Glyco Protein Matrix. This process transforms selenium, yeast and probiotics from a simple admixture into a fully enrobed, food-bound system that greatly improves the absorption of the mineral by the body. 

The tests showed that Selenium+GPM™ was a vastly superior antioxidant than other forms of selenium. Selenium+GPM™ was 64 times better as an antioxidant than selenomethionine.
A clinical bioavailability study conducted at Northridge Hospital Medical Center, an academic affiliate of UCLA, demonstrated that Selenium+GPM™ contained greater clinically significant serum levels than typical selenium ingredients, a key indicator of bioavailability.



As it is shown on the picture selenium values were nearly identical at the start of the study. The GPM product outperformed the USP product at almost every time interval.

PerFem Forte™ contains isoflavones from GMO-Free soybean extract and red clover extract (25 mg aglycone isoflavones).The chemical structure of isoflavones is similar to that of our own estrogen. Because of this similarity, isoflavones can interfere with the action of our own estrogen. 

The risks of excess estrogen can be lowered in this way. Isoflavones can also increase the estrogen activity.
When during menopause the body’s natural level of estrogen drops, isoflavones can compensate this, easing menopause symptoms.

The soy isoflavones are responsible for most of the soy health benefits. The most important soy isoflavones are genistein  and daidzein.
Recent studies have found that soy isoflavones can reduce menopause symptoms such as hot flushes.
Soy isoflavones also appear to reduce cardiovascular disease risk. Isoflavones inhibit the plaque formation on the arteries walls. A review of 38 controlled studies on soy and heart disease concluded that soy is definitely effective for improving cholesterol profile.
Soy isoflavones help in the preservation of the bone substance and help prevent osteoporosis. This is the reason why people in China and Japan very rarely have osteoporosis, despite their low consumption of dairy products, whereas in Europe and North America the contrary happens.
Population-based studies show a strong association between consumption of isoflavones and a reduced risk of breast and endometrial cancer. Women who ate the most soy products and other foods rich in isoflavones reduced their risk of endometrial cancer by 54%.

Modern research has focused on a red clover extract high in isoflavones as a possible treatment for symptoms associated with menopause and cardiovascular health in menopausal women.

Black cohosh is native to North America. Black cohosh was originally used by Native American people in the treatment of many conditions, especially gynecologic disorders.
Most studies of black cohosh have used the standardized extract containing 1 mg of terpene glycosides twice daily. Maximum effect usually occurs in four to eight weeks.
PerFem Forte™ contains the recommended dosage of this herb, which guarantees its efficacy.