Pau d'Arco GP - Research Brief
|I Product Info||I Ingredients
||I Recommended Use
||I Clinical Trials
||I Research Brief
Indication: low immunity, herpetic infection, upper respiratory tract inflammations, influenza prophylaxis, mucous membrane irritation, smoker’s cough, skin conditions.
Actions: immunostimulator, has antiviral, antibacterial and antifungal properties, contains rutin for capillary protection.
Ingredients (per 1 capsule): Pau d’Arco (Tabebuia impetiginosa) bark 4:1 extract (standardized to 3% naphthoquinones) (equivalent to 1400 mg of crude bark) - 350 mg, Rutin – 25 mg.
Low USA domestic & international
Pau d'Arco GP - Research Brief:
Pau d’Arco (Tabebuia impetiginosa) inner bark contains a large amount of chemicals known as quinoids, and a small quantity of benzenoids and flavonoids. These quinoids (and, chiefly, naphthoquinones – lapachol, beta-lapachone etc.) have shown the most documented biological activity.
Researches have shown that lapachol has antitumorous, antiedemic, anti-inflammatory, antiseptic, antiviral, bactericidal, and antifungal activity.
Pau d'arco has demonstrated broad spectrum of actions against a number of disease-causing microorganisms. Antimicrobial properties of many of pau d'arco's active phytochemicals were demonstrated in several clinical studies, in which they exhibited strong “in vitro” activity against bacteria and yeast. Naphthoquinones have antifungal activity. (2)
Tabebuia impetiginosa active constituents have demonstrated “in vitro” antiviral properties against various viruses (including Herpes I and II, influenza, and vesicular stomatitis).
Its antiparasitic actions against various parasites (including malaria, schistosoma, and trypanosoma) have been confirmed as well.
Finally, bark extracts of Pau d'arco have demonstrated anti-inflammatory activity (in mice and rats).
In clinical trials naphthoquinones demonstrated «in vitro» significant activity against cancerous tumors. (3,4) One study reported that lapachol increased the life span of mice inoculated with leukemic cells by over 80%.
Another chemical in Pau d'arco, beta-lapachone, has demonstrated in laboratory studies to have activities similar to lapachol, with few side-effects.