Gemalon™ 500 - Research Brief

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References


Indication: decreased immune response, conditions after surgery and illnesses, intestinal microflora imbalance, prevention of infectious diseases (especially during pregnancy).

Actions: helps support and strengthen the immune system, supports intestinal health, inhibits the growth of pathogenic bacteria, promotes tissue regeneration.

Ingredients: (per 1 tablet):

immunoglobulin IgG (from 45% IgG concentrate) – 250 mg.


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Gemalon™ 500 - Research Brief:

How we get sick, feel achy and run down…

Phase 1

Our body’s immune system defends against infection and illness by releasing immunoglobulin (antibodies.)



Many germs enter our bodies through ingestion. They end up in the 400 sq. feet of GI tract surface area where immunoglobulin works to neutralize the germs.





Phase 2

But, our immune system, weakened from busy lives, stress, aging and crowded conditions doesn’t have the resources to fight germs at point of entry.


The body, now under distress, actually releases less immunoglobulin to the GI tract as it prepares to use its resources elsewhere.






Phase 3

Fewer antibodies decrease our ability to fight and increase our susceptibility to illness.



The germs activate the immune system and trigger inflammatory cytokine production (IL-1, IL-6 and TNF-a.) Cytokines break down body protein into amino acids. The liver processes the amino acids and they are lost as urea until metabolism comes back to normal. We feel achy and run down.





We feel bad for 5 to 7 days, or until the body can produce enough specific antibodies to fight the germs.

Why Oral Supplementation?

The transfer of immunity through oral supplementation is a natural, logical and effective process for obtaining immunity. First, immunoglobulin is the principal anti-infective component of breast-milk and colostrum. In adults, the concentration of immunoglobulin in the digestive tract
and on mucosal surfaces is predictive of the risk of infection (1,2)

Stress and many other conditions increase the risk of infection by reducing immunoglobulin secretion and antibody production. (3,4) Oral immunoglobulin supplementation has been found to help preserve the normal protective barrier of the digestive tract and provide humoral immunity to the gut. (5)

Immune challenge studies are very difficult and expensive to perform on humans, so many of these studies must utilize animal models. Such studies have found that oral immunoprotein supplementation restores appetite, (6,10) reduces inflammation, (10) and promotes improved protein metabolism. (7, 9)

Phase 4

Oral supplementation of Gemalon™ 500 provides immediate support to the immune system.


The all-natural immunoglobulin in Gemalon™ 500 goes to work immediately to neutralize germs. Inflammatory cytokine production is reduced. We feel better within hours! And with continued supplementation, we stay healthy day after day!






The Gut Connection to Good Health

Almost 80% of all disease and infections enter the body either through mucosal tissue or stay localized on mucosal surfaces. Immune cells located in the digestive tract produce tremendous quantities, approximately 5 g per day, of immunoglobulin in the form of secretory IgA, which prevents and resolves infections from any pathogenic organisms (bacteria, viruses and others) and toxins normally found in the gut.

Supplemental immunoglobulins first act in the intestinal tract to eliminate or inhibit the proliferation of disease-causing organisms and toxins. It is this action against invading antigens in the bowel that creates the link between the gut and the rest of the body. The inhibition of the growth of opportunistic organisms or the absorption of toxins by the bowel reduces the stimulation of the immune system. Thus, the body’s resources, particularly amino acids, which would normally be directed towards those challenges, can be redirected to other "battles" in other parts of the body.

Supplementation with immunoglobulins reduces the demand in the gut for naturally produced antibodies. Since the body’s resources are finite, conservation of immune resources in the gut allows more resources to be available wherever else they may be needed.