Echinacea GP - Research Brief

I Product Info I Ingredients I Recommended Use I Clinical Trials I Research Brief I References



Indication: first aid against a common cold, decreased immune response, frequent common colds, flu epidemic.

Actions: increases the body’s natural defense, has anti-inflammatory activity, antioxidant, standardized extract guarantees efficacy.

Ingredients (per 1 capsule):

Echinacea (Echinacea purpurea) 5:1 extract (aerial parts) (4% polyphenolic compounds) (equivalent to 1250 mg of crude herb) - 250 mg, rutin – 25 mg.

Low USA domestic & international



Echinacea GP - Research Brief:

The common cold is probably the most common illness, leading to more doctor visits and absences from school and work than any other illness. Although rhinoviruses and the coronaviruses cause the majority of colds, there are more than 200 viruses that can inflame the membranes in the lining of the nose and throat. (And we probably don't have to remind you how miserable you feel for anywhere from one to 10 days.) Despite the billions of dollars that pharmaceutical companies spend on researching a cure for the common cold, the best they have come up with are products that alleviate symptoms—and usually make you feel drowsy.


Echinacea has been used successfully for hundreds of years as both a preventative and therapeutic treatment option for colds and upper respiratory infections. Although echinacea's popularity waned with the advent of antibiotics, it became respected among herbal practitioners in Europe after the first scientific study in 1932. But it didn't become a popular herb until the early 1980s, when consumers started investigating natural remedies to help immune disorders. Researchers have discovered that Echinacea contain a diverse range of active components affecting different aspects of immune function.


Santegra®’s product Echinacea GP contains aerial parts of Echinacea purpurea rich in polysaccharides, caffeic acid derivatives (chichoric acid), alkamides, essential oils, etc. Analysis of polar fractions of Echinacea purpurea extracts showed the presence of antiviral activity, with evidence suggesting that polyphenolic compounds may be involved. (12)


Studies have shown that chichoric acid has immunostimulating effects, as well as antioxidant properties. he pharmacological activity of polyphenolic compound found in Echinacea includes also disintoxication, regenerative, anti-inflammatory, antitumor, and adaptogenic.

Caffeic acid glucoside increases the defense against infectious and viral diseases, accelerates the recovery.

Polysaccharides, found in Echinacea have immunostimulating and anti-inflammatory properties; stimulate macrophages activity in phagocytosis of bacterias, viruses and dead cells. Polysaccharides promote tissue regeneration, stimulate fibroblasts, and inhibit hyaluronidase, an enzyme secreted by bacteria in order to break down host cell membranes and penetrate the cells. Inhibition of this enzyme may be one of the mechanisms by which Echinacea supplements help prevent infection.


Echinacea promotes nonspecific T-cell activation, a type of white blood cell important in providing resistance to bacteria, yeast, fungi, parasites, and viruses. The T-cells then increase the production of interferon, an important part of the body's response to viral infections.