ProBiotic Complex - intestine microflora

LactoBi ProBiotic Complex - Research Brief

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References

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Indication: dysbacteriosis, constipation, unstable stool, traveler’s diarrhea prophylaxis, damaged intestinal lining, long term drug treatment.

Actions: normalizes intestinal microflora, suppresses pathogenic bacteria, essential after antibiotic therapy, improves digestion and metabolism, strengthens the immune system, recommended for allergy sufferers, contains unique soluble dietary fiber Fibersol 2™.

Ingredients (per one packet – 5.5 g):

Probiotic Blend - 2.3 billion CFU: Bifidobacterium bifidum, Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus casei, Lactobacillus rhamnosus; Calcium (as calcium carbonate) - 40 mg; Xylitol - 50 mg; Fibersol 2 (soluble dietary fiber) - 5000 mg.


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ProBiotic Complex - Research Brief:


Lactobacilli are one of the most important types of friendly bacteria found in the digestive tract. These bacteria get their name (lacto) because they are able to form lactic acid. Lactobacilli help to normalize the balance of the intestine microflora, because the lactic acid creates such environment in the intestines that is not suitable for the survival of the “bad” bacteria.

Lactobacillus acidophilus is the most commonly used probiotic, or "friendly" bacteria. Lactobacilli acidophilus inhabit the intestines and vagina and protect against the entrance and proliferation of "bad" organisms that can cause disease. These bacteria protect urinary tract against Candida albicans, boost the immune system function, and help to restore the balance of intestinal microflora after antibiotic therapy.


Clinical trials show that Lactobacillus casei is effective for treatment of harmful bacterial overgrowth, helps to decrease the duration of diarrhea caused by antibiotic therapy and traveler’s diarrhea. Lactobacillus casei can beneficially alter cholesterol levels and produce a healthier bowel microbial population.


Lactobacillus rhamnosus inhibits the growth of most harmful bacteria in the intestine, effective against diarrhea; helps to remove toxins from the intestines.



Bifidobacteria are one of the major genera of bacteria that make up the gut flora, the bacteria that reside in the colon. Bifidobacteria are a natural part of the bacterial flora in the human body and have a symbiotic bacteria-host relationship with humans. Bifidobacteria improve digestion, help to maintain normal intestinal microflora, aid in the synthesis of the B vitamins.


When you take antibiotics, the "friendly" bacteria in your digestive tract are destroyed along with the harmful bacteria. Bifidobacterium bifidum helps to normalize intestine microflora after antibiotic therapy, strengthens the immune system. Bifidobacterium bifidum helps to improve bowel regularity.

Bifidobacterium longum is among the first bacteria colonizing the intestine of breast-fed infants. Bifidobacterium longum promotes good digestion, boosts the immune system, and promotes bowel regularity. These bacteria produce lactic and acetic acid that helps control intestinal pH, and inhibit the growth of harmful bacteria.


Fibersol 2™

ProBiotic Complex contains Fibersol 2™ - a soluble dietary fiber that is produced from cornstarch by pyrolysis and subsequent enzymatic treatment. Fibersol 2™ is classified as "resistant maltodextrin". One of its benefits is stability to acid and heat/retort processing.

Fibersol 2™ is fermented slowly, thus producing less acid and gas than most soluble dietary fibers. The left picture shows a regular absorption pattern of sugar/starch. The most part of it is absorbed in the stomach. The right picture shows the process of absorption of sugar/starch with Fibersol 2™. Only a small part is digested in the stomach, most of it reaches large intestine and is used as a food for beneficial bacteria, normalizes the intestine microflora, increases the fecal volume.




Fibersol 2™ slows absorption that is beneficial for the blood glucose level and regulates the insulin production (pic.1). It is shown that blood glucose level rise after Fibersol 2™ intake is lower (right diagram).

Ohkuma & Wakabayashi in Advanced Dietary Fiber Technology, 2001, described over ten years of nutritional feeding studies in animals and humans worldwide. 

Fibersol 2™:
Helps maintain healthy blood glucose levels and subsequent insulin response.


Studies indicate that Fibersol 2™ can effectively reduce serum blood glucose level, potentially allowing formulation to be used in foods for diabetics, weight control, and managing serum glucose before, during, and after exercise.
Helps maintain healthy levels of blood triglycerides and serum cholesterol.
Fibersol 2™ significantly reduces levels of blood triglycerides and serum cholesterol. Additionally, Fibersol 2™ effectively retains levels of HDL (good) cholesterol. All this potentially impacts the incidence of coronary heart disease and related diseases.



Fibersol 2™ lowers serum cholesterol levels and triglyceride levels but does not reduce HDL-cholesterol levels.


Helps maintain healthy intestinal regularity.

image3_fortifiBy adding stool volume, moisture, and reducing transit time, Fibersol 2™ helps maintain good colon health, potentially reducing the incidence of various types of colon diseases. In addition, Fibersol 2™ has been shown to prevent atrophy of the lining of the large intestine and does not create excess gas associated with some soluble dietary fibers.

Clinical trial (subjects: 6 males and 14 females prone to constipation) showed that after Fibersol 2™ intake the fecal frequencies increased almost twice.

Fecal frequency study over a 5 day-period: 2.6 times before Fibersol 2™ intake; 4 times after Fibersol 2™ intake (3.75 grams/day).


Helps promote the growth of beneficial bacteria in the colon.


As a water-soluble fiber, Fibersol 2™ can effectively promote the growth of a variety of beneficial bacteria (naturally occurring or ingested as probiotics) in the colon. In promoting the growth of beneficial bacteria, Fibersol 2™ indirectly reduces the presence of undesirable bacterial species.