Vision Forte - Clinical Trials

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References 

visionl

60 tablets/30 days

 

Price: $29.80

 

Actions:

  • provides vitamin-mineral supplemental nutrition for eyes,
  • improves retinal blood circulation,
  • strengthens eye fundus blood vessels,
  • provides antioxidant eye protection,
  • improves color perception,
  • decreases the risk of eye inflammatory diseases.

Indication:

  • decreased vision acuity, night-blindness,
  • work-related eye complaints,
  • frequent inflammatory and allergic eye diseases,
  • decreased eye blood circulation, dysbolism.

Ingredients (per 1 tablet):

  • Vitamin А (100% Beta-carotene) – 4,160 IU,
  • Vitamin С (as ascorbic acid, calcium ascorbate, ascorbyl palmitate,
  • acerola (Malpighia glabra L) 4:1 fruit extract,
  • rose (Rosa rugosa) hips powder – 250 mg,
  • Vitamin E (d-alpha-tocopheryl succinate)  – 90 IU,
  • Zinc (as zinc amino acid chelate) – 12 mg,
  • Selenium (Selenium + GPM™) – 18 mcg,
  • Lutein – 4 mg.

Packaging/Directions:

  • 60 tablets, 1 tablets twice a day.

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Vision Forte - Clinical Trials:

Clinical research demonstrated that 6 mg of lutein a day can lower the risk of macular degeneration by 43%. In people suffering from macular degeneration lutein and zeaxanthin levels in macula retinae area is 40% lower than in healthy people.

The medical trial conducted by Dr. Hammond BR and coworkers showed that the patients who demonstrated the unchanged macular pigment density for the duration of 5 years, had increased macula retinae dencity after 14 weeks of being on the diet rich with lutein and zeaxanthin. And the most importantly this level remained unchanged for another 9 month after carotenoids had been discontinued. (4) 

In 1999, data from the Nurses Health Study showed a reduced likelihood of cataract surgery with increasing intakes of lutein and another carotenoid – zeaxanthin (6 mg/day). (5)

Researchers conducted a double-blind, placebo-controlled trial of lutein. The study enrolled 90 people with dry-type macular degeneration and followed them for 12 months. The participants received either lutein (10 mg), lutein plus other antioxidants, and a multivitamin/mineral supplement, or placebo. At the end of the study period, participants who had taken lutein alone or lutein plus the other nutrients showed improvements in vision, while no change in vision was seen in the placebo group. (6)

Animal toxicology studies have been performed to established lutein's safety as a nutrient. These studies have contributed to the classification of purified crystalline lutein as generally recognized as safe. (7)

The research from the Departments of Epidemiology, Nutrition, and Biostatistics, Harvard School of Public Health, Boston had an objective to examine the association between carotenoid and vitamin A intakes and cataract in men. 36644 US male health professionals who were 45–75 years of age in 1986 were included in this study. A detailed dietary questionnaire was used to assess intake of carotenoids and other nutrients. During 8 years of follow-up, 840 cases of cataract were documented. It observed a modestly lower risk of cataract in men with higher intakes of lutein and zeaxanthin. Men in the highest fifth of lutein and zeaxanthin intake had a 19% lower risk of cataract relative to men in the lowest fifth (relative risk: 0.81; 95% CI: 0.65, 1.01; P for trend = 0.03). Among specific foods high in carotenoids, broccoli and spinach were most consistently associated with a lower risk of cataract. (8)

In the Los Angeles Atherosclerosis Study researchers monitored 480 men and women between ages 40 and 60. Participants had no history of heart disease or stroke. Using ultrasound technology, the researchers measured the thickness of the walls of the carotid (neck) arteries once at the beginning of the study and again 18 months later. They also measured levels of lutein in participants’ blood over the same time span. They found that people whose blood carried the highest levels of lutein averaged only a 0.004 mm increase in the artery thickness over 18 months. In those with the lowest levels of lutein, artery wall thickness increased an average of 0.021 mm.
The second part of the study explored how lutein may protect cells in artery walls. Researchers grew layers of cells from human arteries in a lab, and then exposed them to various combinations of lutein and LDL (or low-density lipoprotein, the so-called "bad" cholesterol known to promote atherosclerosis). They found that arterial cell layers treated with lutein were less prone to starting a process of inflammation related to LDL that leads to atherosclerotic plaque.
In the third part of the study, done with mice, the team found that adding lutein to the diet resulted in the mice having significantly smaller atherosclerotic lesions compared to mice that had no lutein supplementation.
These results support the theory that lutein from food or in supplements has a protective effect on humans against atherosclerosis and cardiovascular disease. (9)