Pau d'Arco GP - References

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References

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Indication: low immunity, herpetic infection, upper respiratory tract inflammations, influenza prophylaxis, mucous membrane irritation, smoker’s cough, skin conditions.

Actions: immunostimulator, has antiviral, antibacterial and antifungal properties, contains rutin for capillary protection.

Ingredients (per 1 capsule):

Pau d’Arco (Tabebuia impetiginosa) bark 4:1 extract (standardized to 3% naphthoquinones) (equivalent to 1400 mg of crude bark) - 350 mg, Rutin – 25 mg.

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Pau d'Arco GP - References:

  1. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 470-1.

  2. Guiraud P, Steiman R, Campos-Takaki GM, et al. Comparison of antibacterial and antifungal activities of lapachol and beta-lapachone. Planta Med 1994;60:373-4.

  3. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. Binghamton, NY: Pharmaceutical Products Press, 1994, 180.

  4. Oswald EH. Lapacho. Br J Phytother 1993/4;3:112-7.

  5. Kung HN, Yang MJ, Chang CF, Chau YP, Lu KS. In vitro and in vivo wound healing-promoting activities of beta-lapachone. Am J Physiol Cell Physiol. 2008 Oct;295(4):C931-43. Epub 2008 Jul 23.

  6. Son DJ, Lim Y, Park YH, Chang SK, Yun YP, Hong JT, Takeoka GR, Lee KG, Lee SE, Kim MR, Kim JH, Park BS. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular smooth muscle cell proliferation through suppressions of arachidonic acid liberation and ERK1/2 MAPK activation. J Ethnopharmacol. 2006 Nov 3;108(1):148-51.

  7. Park BS, Lee HK, Lee SE, Piao XL, Takeoka GR, Wong RY, Ahn YJ, Kim JH. Antibacterial activity of Tabebuia impetiginosa Martius ex DC (Taheebo) against Helicobacter pylori. J Ethnopharmacol. 2006 Apr 21;105(1-2):255-62. Epub 2005 Dec 15.

  8. Park BS, Lee KG, Shibamoto T, Lee SE, Takeoka GR. Antioxidant activity and characterization of volatile constituents of Taheebo (Tabebuia impetiginosa Martius ex DC). J Agric Food Chem. 2003 Jan 1;51(1):295-300.

  9. Bezerra DP, Alves AP, de Alencar NM, Mesquita Rde O, Lima MW, Pessoa C, de Moraes MO, Lopes JN, Lopes NP, Costa-Lotufo LV. Antitumor activity of two derivatives from 2-acylamine-1, 4-naphthoquinone in mice bearing S180 tumor. J Exp Ther Oncol. 2008;7(2):113-21.

  10. Balassiano IT, De Paulo SA, Henriques Silva N, Cabral MC, da Gloria da Costa Carvalho M. Demonstration of the lapachol as a potential drug for reducing cancer metastasis. Oncol Rep. 2005 Feb;13(2):329-33.

  11. Tandon VK, Singh RV, Yadav DB. Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2901-4.

  12. Schmeda-Hirschmann, G.; Papastergiou, F.Z. Naturforsch. 2003, 58c, 495.

  13. Pinto CN, Dantas AP, De Moura KC, Emery FS, Polequevitch PF, Pinto MC, de Castro SL, Pinto AV. Chemical reactivity studies with naphthoquinones from Tabebuia with anti-trypanosomal efficacy. Arzneimittelforschung. 2000 Dec;50(12):1120-8.