MenoFix™ - Clinical Trials

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References

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Indication: premenstrual syndrome, hormonal imbalance, estrogen deficiency, menstrual irregularities.

Actions: helps normalize female hormonal  balance, reduces the premenstrual syndrome (PMS)  symptoms, supports the health of female reproductive system, strengthens the nervous system, vitamin and mineral support for women’s health.

Ingredients (per 1 capsule):

vitamin A (as beta carotene) – 2000 IU, vitamin C (as ascorbic acid, calcium ascorbate, ascorbyl palmitate, acerola (Malpighia glabra L) 4:1 fruit extract, rose hips (Rosa rugosa) powder)  – 30 mg, vitamin E (as d-alfa-tocopheryl succinate) – 15 IU, thiamin (as thiamin HCl) – 2 mg, riboflavin – 0.9 mg, niacin (as niacin and niacinamide) – 15 mg, vitamin B6 (as pyridoxine HCl) – 3 mg, folate – 200 mcg, vitamin B12 (as cyanocobalamin) – 2.5 mcg, iron (as carbonyl iron) – 7 mg, iodine (from Ascophyllum nodosum) – 50 mcg, zinc (as zinc citrate) – 7.5 mg, selenium (as selenium + GPM) – 35 mcg, copper (as copper gluconate)– 1 mg, black cohosh (Cimicifuga racemosa)) (12:1) root extract [8% triterpene glycosides (as 27-deoxyactein)] (equivalent to 78 mg of crude herb) – 6.5 mg, chaste tree (Vitex agnus-castus) berry extract (4:1) (0.5% total agnusides and 0.15% aucubin) (equivalent to 1000 mg of crude herb) – 250 mg.

  

MenoFix™ - Clinical Trials:

A review of clinical trials and case reports suggests there is at least preliminary support that vitex should be considered for women with irregular periods, infertility, and mildly elevated prolactin levels. (7)

Double-blind trials have confirmed the effectiveness of vitex at lowering mildly elevated prolactin levels in women. (8)

According to one trial, acne associated with PMS, may be reduced using vitex. (9)

Another clinical trial showed that 10 from 15 women, suffering from amenorrhoea reported the improvement in menstrual regularity after 6 months of taking 40 drops of vitex fluid extract. (10)

Animal trial showed that vitex inhibited prolactin secretion in rats. (11)

A controlled clinical trial found that women taking 20 mg per day of a concentrated vitex extract for three menstrual cycles had a significant reduction in symptoms of PMS, including irritability, mood swings, headache, and breast tenderness. (12)

There have been two large surveys done in Germany to study the effect of vitex on 1542 women diagnosed as suffering from PMS. The trial lasted for 166 days using vitex fluid extract. The treatment was assessed by both patient and practitioner and in 90% of cases symptoms were completely relieved. Physical symptoms such as headaches, sore breasts, bloating, fatigue and psychological changes such as increased appetite, sweet cravings, nervousness, anxiety, depression, mood swings and lack of concentration were all reduced. It was noted that improvement in symptoms began on average after 25 days. (13)

Vitex was used by 45 infertile women between the ages of 23 and 39. The women were considered capable of reproduction and had normal prolactinaemia but showed pathologically low serum levels at day 20 of the menstrual cycle. After three months of vitex treatment seven women became pregnant, 25 had normal serum progesterone levels at day 20 and another 7 tended toward normal. This generally coincides with a lengthening of the luteal phase and a positive change in the LHRH test dynamic. The findings indicate an enhancement of corpus luteal function. (14)