Gotu Kola GP - Research Brief

I Product Info I Ingredients
I Recommended Use
I Clinical Trials
I Research Brief
I References

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Indication: brain circulation impairment, impaired memory, dizziness, varicose veins, menopausal syndrome, sleep disturbance, nervousness, stress, wounds, burns, cuts, cosmetic surgery.

Main Actions: supports mental functions, memory and concentration, improves brain and peripheral circulation, helps to lower intracranial pressure, improves symptoms of varicose veins, speeds up healing processes, mild sedative effect.

Ingredients:(per 1 capsule):

standardized Gotu kola (Centella asiatica) leaf 12:1 extract (10% asiaticosides – 15 mg) (equivalent to 1800 mg of crude herb) - 150 mg.

 

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Gotu Kola GP - Research Brief:

Gotu kola is a perennial plant native to India, Japan, China, Indonesia, South Africa, Sri Lanka, and the South Pacific. It is tasteless and odorless and thrives in and around water. It has small fan-shaped green leaves with white or light purple-to-pink flowers, and it bears small oval fruit. The leaves and stems of the Gotu kola plant are used for medicinal purposes.

The active compounds of Gotu kola were first isolated in the early 1940's. (1)
Gotu kola
contains a variety of biologically active chemical groups; it contains triterpenoid glycosides (saponines) , phytosterols and a volatile oil consisting of vallerin, camphor, cineole. Vitamins B and C, Е, К, tannins, several aminoacids, Ca, Mg and Na1.
The triterpenoid glycosides include asiaticoside, asiatoside, asiatic acid, madecassic acid, madicassoside, oxyasiaticoside, brahminoside, brahmoside, centelloside

The active ingredients of Gotu kola were determined to be triterpenoids.

Gotu Kola GP contains standardized Gotu kola (Centella asiatica) leaf 12:1 extract (10% asiaticosides).

Triterpenoids appear to have antioxidant benefits and an ability to stimulate collagen and glycosaminoglycan synthesis for tissue regeneration.

Flavonoids help to improve blood flow, has antispasmodic action on the blood vessels, strengthen the vascular walls, and help to lower intracranial pressure.

Madecassosides has strong anti-inflammatory properties.

Due mostly to the actions of chemicals known as asiaticosides and madecassosidesGotu kola may prevent, delay, and treat a condition known as chronic venous insufficiency. Asiaticosides and madecassosides help support veins and other blood vessels. Gotu kola strengthens the collagen lining of vein walls, enhances circulation, and reduces inflammation in varicose veins.  It may also help to relieve hemorrhoids.

Brahminosides and  brahmosides has mild diuretic and calming properties.

In recent animal studies, oral Gotu kola has been shown to have anticonvulsant, pain-relieving, and sedative effects. All of these central nervous system effects are thought to be related to increased levels of gamma aminobutyric acid (GABA) that are associated with taking Gotu kola. GABA is a neurotransmitter (a chemical that carries messages from nerve cells to other cells) that helps to regulate the speed of nerve cell firing. GABA is also known to help prevent seizures and promote relaxation. 

Gotu kola helps stimulate nervous system, restore energy. Triterpenoids take part in transmission of nerve signals in the brain, thus improving the function of the central nervous system. Nervous system is supported also due to the high content of vitamin B in this plant, which also helps to transform food into energy.
Gotu kola gently stimulates nervous system. It makes you feel more alert, but without over-stimulating as caffeine does, meaning that you aren't left feeling jittery and anxious.

The herb has also been shown to alleviate stress, anxiety, mental fatigue, and memory problems. (2)
It helps to stimulate brain cell metabolism and protects your cells against possible damage from toxins. (3)