ExPress Essentials - References

I Product Info I Ingredients I Recommended Use I Clinical Trials I Research Brief I References

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Indication: hormone related disease prophylaxis; body’s protection and recovery after intoxication, alcohol abuse; polluted working environment; allergies; unbalanced diet; constipation.

Actions: potent antioxidant, lowers the risk of developing certain types of cancer, helps to regulate metabolism and hormonal balance, detoxifies the body, contains standardized cruciferous vegetable blend with guaranteed active ingredients (2% glucosinolates).

Ingredients (per 1 packet):

 

Cruciferous Blend (kale, brussels sprouts, cabbages, broccoli, mustard and horseradish) (providing 2% glucosinolates) - 400 mg, Indole-3-Carbinol - 35mg.

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ExPress Essentials - References:

1. Stoewsand GS. Bioactive organosulfur phytochemicals in Brassica oleracea vegetables—a review. Food Chem Toxicol 1995;33:537–43.
2. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part I]. Curr Med Chem  1998;5:337–52.
3. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part II]. Curr Med Chem 1998;5:469–91.
4. Int J Vitam Nutr Res. 2002 Jan;72(1):26-31.
5. Michnovicz, J.J. and H.L. Bradlow. (1990). "Induction of estradiol metabolism by dietary indole-3-carbinol in humans." Journal of the National Cancer Institute. 82. 947-9. 
6. Michaud DS et al, 1999. Fruit and vegetable intake and incidence of bladder cancer in a male   prospective cohort. J Natl Cancer Inst 91:605-613.
7. Zhang SM et al, 2000. Intakes of fruits, vegetables, and related nutrients and the risk of non-Hodgkin’s lymphoma among women. Cancer Epidemiol Biomarkers Prev 9:477-485.
8. Cohen JH et al, 2000. Fruit and vegetable intakes and prostate cancer risk. J Natl Cancer Inst 92:61-68.
9. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Indole-3-carbinol. A novel approach to breast cancer prevention. Ann N Y Acad Sci 1995;768:180–200.
10. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent. Ann N Y Acad Sci 1999;889:204–13.
11. Bell MC, Crowley-Nowick P, Bradlow HL, et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol Oncol 2000;78:123–9.
12. Michnovicz JJ. Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol. Int J Obes Relat Metab Disord 1998;22:227–9.
13. Von Poppel, G., Verhoeven, D. T., Verhagen, H. & Goldbohm, R. A. (1999) Brassica vegetables and cancer prevention. Epidemiology and mechanisms. Adv. Exp. Med. Biol. 472: 159–168.
14. Mukherjee S, Gangopadhyay H, Das DK. Broccoli: A Unique Vegetable That Protects Mammalian Hearts through the Redox Cycling of the Thioredoxin Superfamily. J Agric Food Chem. 2008 Jan 23;56(2):609-17. Epub 2007 Dec 29.
15. Souli E, Machluf M, Morgenstern A, Sabo E, Yannai S. Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice. Food Chem Toxicol. Epub 2007 Oct 30.
16. Sung WS, Lee DG. In vitro antimicrobial activity and the mode of action of indole-3-carbinol against human pathogenic microorganisms.Biol Pharm Bull. 2007 Oct;30(10):1865-9.
17. Park MK, Rhee YH, Lee HJ, Lee EO, Kim KH, Park MJ, Jeon BH, Shim BS, Jung CH, Choi SH, Ahn KS, Kim SH. Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo.Phytother Res. 2008 Jan;22(1):58-64.